Role of oral sodium phosphate and its effectiveness in large bowel preparation for out-patient colonoscopy

Abstract

The aim of our study was to determine the tolerance and efficacy of oral sodium phosphate compared with polyethylene glycol electrolyte (PEG) solution on out-patient colonoscopy. Seventy-nine patients (35 male, 44 female) for elective out-patient colonoscopy were randomized to receive either PEG (GoLYTELY) solution or oral sodium phosphate (Fleet Phospho-Soda) before the procedure. Patients subsequently completed a questionnaire to assess tolerance to either regimen. The endoscopists, who were blinded to the type of bowel preparation, assessed the results in terms of residual faecal content and percentage of bowel wall visualized. Sixty-seven per cent (26) of 39 patients found Phospho-Soda easy to complete, compared with 53% (21) of 40 patients with PEG (P = 0.06). There was no statistical significance between the two groups in terms of symptomatology. Colonoscopic assessment of the Phospho-Soda group showed better cleansing compared to the PEG group at all levels of the colon (P = 0.02-0.002). Phospho-Soda is just as well tolerated as a standard PEG regimen and provides better cleansing of the bowel for colonoscopy.