Please use this identifier to cite or link to this item:
https://doi.org/10.1016/S0020-7292(97)00072-6
Title: | Responses of polycystic ovarian syndrome and related variants to low-dose follicle stimulating hormone | Authors: | Yong, E.L. Ng, S.C. Chan, C. Kumar, J. Teo, L.S. Ratnam, S. |
Keywords: | Chronic low-dose FSH Polycystic ovarian syndrome Polycystic ovarian syndrome-like |
Issue Date: | Jun-1997 | Citation: | Yong, E.L., Ng, S.C., Chan, C., Kumar, J., Teo, L.S., Ratnam, S. (1997-06). Responses of polycystic ovarian syndrome and related variants to low-dose follicle stimulating hormone. International Journal of Gynecology and Obstetrics 57 (3) : 305-311. ScholarBank@NUS Repository. https://doi.org/10.1016/S0020-7292(97)00072-6 | Abstract: | Objective: To determine whether patients with classical polycystic ovarian syndrome (PCOS) respond differently to low-dose FSH therapy in comparison with anovulatory patients (PCOS-like) where only some features of PCOS are present. Methods: Two groups of patients were studied. The PCOS group (25 patients, 51 cycles) and the PCOS-like group (38 patients, 57 cycles) were treated with the same protocol of purified FSH, commencing with an initial dosage of 75 IU/day and increasing by 37.5 IU/day after 14 days, where necessary. Estradiol levels and ultrasonographic evidence of follicular development were used for monitoring. Results: PCOS patients required more ampules of FSH, needed more days of gonadotropin stimulation, secreted higher levels of E2 and had increased numbers of intermediate follicles compared to the PCOS-like group. Conclusions: This study demonstrated significant differences between PCOS and other PCOS-like conditions when treated with low-dose FSH. Classification of the subvariants of PCOS may have therapeutic implications. | Source Title: | International Journal of Gynecology and Obstetrics | URI: | http://scholarbank.nus.edu.sg/handle/10635/133767 | ISSN: | 00207292 | DOI: | 10.1016/S0020-7292(97)00072-6 |
Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.