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https://scholarbank.nus.edu.sg/handle/10635/133254
| Title: | In vitro C-20, 22 desmolase regulation of pregnenolone supply in first trimester human placenta | Authors: | Gunasegaram, R. Peh, K.L. Chew, P.C.T. Karim, S.M. Ratnam, S.S. |
Issue Date: | 1979 | Citation: | Gunasegaram, R., Peh, K.L., Chew, P.C.T., Karim, S.M., Ratnam, S.S. (1979). In vitro C-20, 22 desmolase regulation of pregnenolone supply in first trimester human placenta. Acta Endocrinologica 90 (1) : 185-192. ScholarBank@NUS Repository. | Abstract: | Homogenates of first trimester human placentae were incubated with [26-14C]cholesterol. Using reverse-isotope dilution analysis [14C]isocaproic acid was isolated and characterized. A progressive increase in [14C]isocaproic acid formation with increasing gestation suggestive of a regulatory mechanism at the C-20, 22 desmolase site in the supply of placental pregnenolone was noted. | Source Title: | Acta Endocrinologica | URI: | http://scholarbank.nus.edu.sg/handle/10635/133254 | ISSN: | 00015598 |
| Appears in Collections: | Staff Publications |
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