Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/133254
Title: In vitro C-20, 22 desmolase regulation of pregnenolone supply in first trimester human placenta
Authors: Gunasegaram, R.
Peh, K.L.
Chew, P.C.T.
Karim, S.M.
Ratnam, S.S. 
Issue Date: 1979
Source: Gunasegaram, R., Peh, K.L., Chew, P.C.T., Karim, S.M., Ratnam, S.S. (1979). In vitro C-20, 22 desmolase regulation of pregnenolone supply in first trimester human placenta. Acta Endocrinologica 90 (1) : 185-192. ScholarBank@NUS Repository.
Abstract: Homogenates of first trimester human placentae were incubated with [26-14C]cholesterol. Using reverse-isotope dilution analysis [14C]isocaproic acid was isolated and characterized. A progressive increase in [14C]isocaproic acid formation with increasing gestation suggestive of a regulatory mechanism at the C-20, 22 desmolase site in the supply of placental pregnenolone was noted.
Source Title: Acta Endocrinologica
URI: http://scholarbank.nus.edu.sg/handle/10635/133254
ISSN: 00015598
Appears in Collections:Staff Publications

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