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|Title:||In vitro C-20, 22 desmolase regulation of pregnenolone supply in first trimester human placenta|
|Citation:||Gunasegaram, R., Peh, K.L., Chew, P.C.T., Karim, S.M., Ratnam, S.S. (1979). In vitro C-20, 22 desmolase regulation of pregnenolone supply in first trimester human placenta. Acta Endocrinologica 90 (1) : 185-192. ScholarBank@NUS Repository.|
|Abstract:||Homogenates of first trimester human placentae were incubated with [26-14C]cholesterol. Using reverse-isotope dilution analysis [14C]isocaproic acid was isolated and characterized. A progressive increase in [14C]isocaproic acid formation with increasing gestation suggestive of a regulatory mechanism at the C-20, 22 desmolase site in the supply of placental pregnenolone was noted.|
|Source Title:||Acta Endocrinologica|
|Appears in Collections:||Staff Publications|
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