Please use this identifier to cite or link to this item: https://doi.org/10.1159/000114300
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dc.titlePositive association between plasma homocysteine level and chronic kidney disease
dc.contributor.authorShankar, A.
dc.contributor.authorWang, J.J.
dc.contributor.authorChua, B.
dc.contributor.authorRochtchina, E.
dc.contributor.authorFlood, V.
dc.contributor.authorMitchell, P.
dc.date.accessioned2016-12-13T05:36:33Z
dc.date.available2016-12-13T05:36:33Z
dc.date.issued2008-02
dc.identifier.citationShankar, A., Wang, J.J., Chua, B., Rochtchina, E., Flood, V., Mitchell, P. (2008-02). Positive association between plasma homocysteine level and chronic kidney disease. Kidney and Blood Pressure Research 31 (1) : 55-62. ScholarBank@NUS Repository. https://doi.org/10.1159/000114300
dc.identifier.issn14204096
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/132789
dc.description.abstractBackground: Increasing experimental evidence, including recently developed animal models, supports a role for homocysteine in the development of chronic kidney disease (CKD). However, relatively few clinical/epidemiological studies have examined this hypothesis in humans. We examined the relationship between plasma homocysteine level and CKD in a population-based study of older Australians. Methods: Community-based study (1992-1994) among 2,609 individuals (58.6% women), aged 49-98 years, free of clinical cardiovascular disease in the Blue Mountains region, west of Sydney, Australia. The main outcome-of-interest was CKD (n = 461), defined as estimated glomerular filtration rate of 14 μmol/l) to quartile 1 (≤9 μmol/l) was 10.44 (6.99-15.60), p-trend
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1159/000114300
dc.sourceScopus
dc.subjectBlue Mountains Eye Study
dc.subjectChronic kidney disease
dc.subjectHypertension
dc.subjectPlasma homocysteine
dc.typeArticle
dc.contributor.departmentCOMMUNITY,OCCUPATIONAL & FAMILY MEDICINE
dc.description.doi10.1159/000114300
dc.description.sourcetitleKidney and Blood Pressure Research
dc.description.volume31
dc.description.issue1
dc.description.page55-62
dc.description.codenKBPRF
dc.identifier.isiut000253015300007
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