Please use this identifier to cite or link to this item:
Title: Nerve anastomosis with glue: Comparative histologic study of fibrin and cyanoacrylate glue
Authors: Wieken, K.
Angioi-Duprez, K.
Lim, A. 
Marchal, L.
Merle, M.
Keywords: Cyanocrylate
Nerve repair
Issue Date: Jan-2003
Citation: Wieken, K., Angioi-Duprez, K., Lim, A., Marchal, L., Merle, M. (2003-01). Nerve anastomosis with glue: Comparative histologic study of fibrin and cyanoacrylate glue. Journal of Reconstructive Microsurgery 19 (1) : 17-20. ScholarBank@NUS Repository.
Abstract: The authors report the results of a comparative experimental nerve study, using a biologic tissue glue (fibrin) and a synthetic glue (2-cyanoacrylate) in a rat model. A tension-free repair is necessary with the use of fibrin glue, or gapping may occur, thus limiting the use of the agent in promoting re-neurotization. In addition, the human origin of fibrin and thrombin allow for the possibility of viral transmission. The aim of the study was to verify if the synthetic glue is a viable alternative, or whether it causes cellular and tissue lesions. Their main finding was that the cyanoacrylate causes a foreign-body inflammatory reaction and retractile fibrosis, often reducing the nerve diameter up to two-thirds. Cyanoacrylate glue is thus not recommended for peripheral nerve repair.
Source Title: Journal of Reconstructive Microsurgery
ISSN: 0743684X
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

checked on Nov 24, 2022

Google ScholarTM


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.