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Title: Validation of the chinese SF-36 for quality of life assessment in patients with systemic lupus erythematosus
Authors: Thumboo, J. 
Feng, P.-H. 
Boey, M.-L. 
Soh, C.-H.
Thio, S.-T.
Fong, K.-Y. 
Keywords: Asia
Quality of life
Systemic lupus erythematosus
Issue Date: 2000
Citation: Thumboo, J., Feng, P.-H., Boey, M.-L., Soh, C.-H., Thio, S.-T., Fong, K.-Y. (2000). Validation of the chinese SF-36 for quality of life assessment in patients with systemic lupus erythematosus. Lupus 9 (9) : 708-712. ScholarBank@NUS Repository.
Abstract: We studied the reliability and validity of the Chinese Short-Form 36 Health Survey (SF-36) in a cross sectional study of patients with systemic lupus erythematosus (SLE). Sixty-nine consecutive subjects completed a questionnaire containing the Chinese SF-36 twice within 14 d. Disease activity and damage were assessed using the British Isles Lupus Activity Group (BILAG) and SLICC/ACR Damage Index (DI) scales, respectively. Internal consistency was assessed using Cronbach's alpha, reliability using Spearman's correlation and repeatability coefficients, and relationships between SF-36, BILAG and DI scores using Spearman's correlation. The Chinese SF-36 showed high internal consistency (α= 0.72-0.91) and good reliability, with correlations exceeding 0.70 for 7 scales and mean scale score differences of < 2 points for 6 scales. SF-36 scores correlated weakly with BILAG scores (-0.27 to -0.41) and DI scores (-0.24 to -0.35), and subjects' mean SF-36 scores were 6-24 points lower than the general population, supporting construct validity of the SP-36. These data suggest that the Chinese SF-36 is a reliable and valid measure of quality of life in patients with SLE.
Source Title: Lupus
ISSN: 09612033
DOI: 10.1191/096120300673421268
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