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|Title:||C-type natriuretic peptide (CNP) signal peptide fragments are present in the human circulation||Authors:||Pemberton, C.J.
|Issue Date:||2014||Citation:||Pemberton, C.J., Siriwardena, M., Kleffmann, T., Richards, A.M. (2014). C-type natriuretic peptide (CNP) signal peptide fragments are present in the human circulation. Biochemical and Biophysical Research Communications. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bbrc.2014.05.020||Abstract:||Background: Signal peptides may be novel biomarkers in cardiovascular diseases. Methods: We developed a novel immunoassay to the signal peptide of preproCNP (CNPsp) and used this to document circulating venous concentrations of CNPsp in normal healthy volunteers (n = 109), regional plasma CNPsp concentrations in patients undergoing clinically indicated catheterisation (n = 24) and temporal CNPsp concentrations in patients with ST-elevation myocardial infarction (STEMI)||Source Title:||Biochemical and Biophysical Research Communications||URI:||http://scholarbank.nus.edu.sg/handle/10635/126880||ISSN:||0006291X||DOI:||10.1016/j.bbrc.2014.05.020|
|Appears in Collections:||Staff Publications|
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