Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.bbrc.2014.05.020
Title: C-type natriuretic peptide (CNP) signal peptide fragments are present in the human circulation
Authors: Pemberton, C.J.
Siriwardena, M.
Kleffmann, T.
Richards, A.M. 
Keywords: Biomarkers
CNP
Mass spectrometry
Myocardial infarction
Signal peptide
Issue Date: 2014
Citation: Pemberton, C.J., Siriwardena, M., Kleffmann, T., Richards, A.M. (2014). C-type natriuretic peptide (CNP) signal peptide fragments are present in the human circulation. Biochemical and Biophysical Research Communications. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bbrc.2014.05.020
Abstract: Background: Signal peptides may be novel biomarkers in cardiovascular diseases. Methods: We developed a novel immunoassay to the signal peptide of preproCNP (CNPsp) and used this to document circulating venous concentrations of CNPsp in normal healthy volunteers (n = 109), regional plasma CNPsp concentrations in patients undergoing clinically indicated catheterisation (n = 24) and temporal CNPsp concentrations in patients with ST-elevation myocardial infarction (STEMI)
Source Title: Biochemical and Biophysical Research Communications
URI: http://scholarbank.nus.edu.sg/handle/10635/126880
ISSN: 0006291X
DOI: 10.1016/j.bbrc.2014.05.020
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