Please use this identifier to cite or link to this item: https://doi.org/10.5897/AJB11.1302
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dc.titleDetection of mycobacterial antibodies in serum samples by enzyme linked immunosorbent assay
dc.contributor.authorNath, S.S.
dc.contributor.authorNathiya, K.
dc.contributor.authorDhanabalan, R.
dc.contributor.authorAngayarkanni, J.
dc.contributor.authorPalaniswamy, M.
dc.date.accessioned2016-06-02T10:29:41Z
dc.date.available2016-06-02T10:29:41Z
dc.date.issued2011-11
dc.identifier.citationNath, S.S., Nathiya, K., Dhanabalan, R., Angayarkanni, J., Palaniswamy, M. (2011-11). Detection of mycobacterial antibodies in serum samples by enzyme linked immunosorbent assay. African Journal of Biotechnology 10 (71) : 16012-16015. ScholarBank@NUS Repository. https://doi.org/10.5897/AJB11.1302
dc.identifier.issn16845315
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/125007
dc.description.abstractTuberculosis (TB) is a common and deadly infectious disease caused by Mycobacterium tuberculosis and rarely by other subspecies of the M. tuberculosis complex, such as Mycobacterium bovis. Enzymelinked immunosorbent assay (ELISA) for diagnosis of tuberculosis has been widely explored over the years. The purpose of this study was to reduce the time duration required for the diagnosis of tuberculosis. We have extracted antigens from the M. tuberculosis strain H37Ra. Antibody response was studied using ELISA. A total of 30 samples were analysed for their specificity and sensitivity. Of which, 20 were positive and the sensitivity and specificity of the test appeared to be 89%. The high sensitivities, specificities and promising antigenic combination in detection of TB suggest their potential application in diagnosis of TB. © 2011 Academic Journals.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.5897/AJB11.1302
dc.sourceScopus
dc.subjectEnzyme-linked immunosorbent assay (ELISA)
dc.subjectMycobacterial antigens
dc.subjectTuberculosis
dc.typeArticle
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.doi10.5897/AJB11.1302
dc.description.sourcetitleAfrican Journal of Biotechnology
dc.description.volume10
dc.description.issue71
dc.description.page16012-16015
dc.identifier.isiut000299739400024
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