Please use this identifier to cite or link to this item: https://doi.org/10.1111/opo.12212
Title: Eye size and shape in newborn children and their relation to axial length and refraction at 3 years
Authors: Lim, Shen Laurence 
Chua, Sharon
Tan, Pei Ting 
Cai, Shirong 
Chong, Yap Seng 
Kwek, Yung Chiang Kenneth 
Gluckman, Peter D. 
Fortier, Marielle V.
Ngo, Shufen Cheryl 
Qiu, Anqi 
Saw, Seang-Mei 
Keywords: Imaging
Magnetic resonance imaging
Myopia
Ocular development
Issue Date: 1-Jul-2015
Publisher: Wiley
Citation: Lim, Shen Laurence, Chua, Sharon, Tan, Pei Ting, Cai, Shirong, Chong, Yap Seng, Kwek, Yung Chiang Kenneth, Gluckman, Peter D., Fortier, Marielle V., Ngo, Shufen Cheryl, Qiu, Anqi, Saw, Seang-Mei (2015-07-01). Eye size and shape in newborn children and their relation to axial length and refraction at 3 years. Ophthalmic and Physiological Optics 35 (4) : 414-423. ScholarBank@NUS Repository. https://doi.org/10.1111/opo.12212
Abstract: Purpose: To determine if eye size and shape at birth are associated with eye size and refractive error 3 years later. Methods: A subset of 173 full-term newborn infants from the Growing Up in Singapore Towards healthy Outcomes (GUSTO) birth cohort underwent magnetic resonance imaging (MRI) to measure the dimensions of the internal eye. Eye shape was assessed by an oblateness index, calculated as 1 - (axial length/width) or 1 - (axial length/height). Cycloplegic autorefraction (Canon Autorefractor RK-F1) and optical biometry (IOLMaster) were performed 3 years later. Results: Both eyes of 173 children were analysed. Eyes with longer axial length at birth had smaller increases in axial length at 3 years (p < 0.001). Eyes with larger baseline volumes and surface areas had smaller increases in axial length at 3 years (p < 0.001 for both). Eyes which were more oblate at birth had greater increases in axial length at 3 years (p < 0.001). Using width to calculate oblateness, prolate eyes had smaller increases in axial length at 3 years compared to oblate eyes (p < 0.001), and, using height, prolate and spherical eyes had smaller increases in axial length at 3 years compared to oblate eyes (p < 0.001 for both). There were no associations between eye size and shape at birth and refraction, corneal curvature or myopia at 3 years. Conclusions: Eyes that are larger and have prolate or spherical shapes at birth exhibit smaller increases in axial length over the first 3 years of life. Eye size and shape at birth influence subsequent eye growth but not refractive error development. © 2015 The College of Optometrists.
Source Title: Ophthalmic and Physiological Optics
URI: http://scholarbank.nus.edu.sg/handle/10635/121071
ISSN: 02755408
DOI: 10.1111/opo.12212
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
2015-eye_size_shape_newborn_children-published.pdf391.04 kBAdobe PDF

CLOSED

Published

SCOPUSTM   
Citations

15
checked on Mar 6, 2021

WEB OF SCIENCETM
Citations

12
checked on Feb 24, 2021

Page view(s)

323
checked on Mar 6, 2021

Download(s)

246
checked on Mar 6, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.