Please use this identifier to cite or link to this item:
|Title:||Complete circular DNA in the mitochondria-like organelles of Blastocystis hominis||Authors:||Wawrzyniak, I.
El Alaoui, H.
Circular DNA molecule
|Issue Date:||Oct-2008||Citation:||Wawrzyniak, I., Roussel, M., Diogon, M., Couloux, A., Texier, C., Tan, K.S.W., Vivarès, C.P., Delbac, F., Wincker, P., El Alaoui, H. (2008-10). Complete circular DNA in the mitochondria-like organelles of Blastocystis hominis. International Journal for Parasitology 38 (12) : 1377-1382. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ijpara.2008.06.001||Abstract:||Blastocystis hominis is an anaerobic parasite of the human intestinal tract belonging to the Stramenopile group. Using genome sequencing project data, we describe here the complete sequence of a 29,270-bp circular DNA molecule that presents mitochondrial features (such as oxidative phosphorylation complex I subunits) but lacks complexes III, IV and V. Transmission electron microscopy analyses reveal that this molecule, as well as mitochondrial (NADH:ubiquinone oxidoreductase subunit 7 (NAD7), β-succinyl-CoA synthetase (β-SCS)) and hydrogenosomal (pyruvate ferredoxin oxido-reductase (PFOR), iron-hydrogenase) proteins, are located within double-membrane surrounded-compartments known as mitochondria-like organelles (MLOs). As there is no evidence for hydrogen production by this organism, we suggest that MLOs are more likely anaerobic mitochondria. © 2008 Australian Society for Parasitology Inc.||Source Title:||International Journal for Parasitology||URI:||http://scholarbank.nus.edu.sg/handle/10635/120835||ISSN:||00207519||DOI:||10.1016/j.ijpara.2008.06.001|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.