Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ijpara.2008.06.001
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dc.titleComplete circular DNA in the mitochondria-like organelles of Blastocystis hominis
dc.contributor.authorWawrzyniak, I.
dc.contributor.authorRoussel, M.
dc.contributor.authorDiogon, M.
dc.contributor.authorCouloux, A.
dc.contributor.authorTexier, C.
dc.contributor.authorTan, K.S.W.
dc.contributor.authorVivarès, C.P.
dc.contributor.authorDelbac, F.
dc.contributor.authorWincker, P.
dc.contributor.authorEl Alaoui, H.
dc.date.accessioned2015-09-10T04:32:11Z
dc.date.available2015-09-10T04:32:11Z
dc.date.issued2008-10
dc.identifier.citationWawrzyniak, I., Roussel, M., Diogon, M., Couloux, A., Texier, C., Tan, K.S.W., Vivarès, C.P., Delbac, F., Wincker, P., El Alaoui, H. (2008-10). Complete circular DNA in the mitochondria-like organelles of Blastocystis hominis. International Journal for Parasitology 38 (12) : 1377-1382. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ijpara.2008.06.001
dc.identifier.issn00207519
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/120835
dc.description.abstractBlastocystis hominis is an anaerobic parasite of the human intestinal tract belonging to the Stramenopile group. Using genome sequencing project data, we describe here the complete sequence of a 29,270-bp circular DNA molecule that presents mitochondrial features (such as oxidative phosphorylation complex I subunits) but lacks complexes III, IV and V. Transmission electron microscopy analyses reveal that this molecule, as well as mitochondrial (NADH:ubiquinone oxidoreductase subunit 7 (NAD7), β-succinyl-CoA synthetase (β-SCS)) and hydrogenosomal (pyruvate ferredoxin oxido-reductase (PFOR), iron-hydrogenase) proteins, are located within double-membrane surrounded-compartments known as mitochondria-like organelles (MLOs). As there is no evidence for hydrogen production by this organism, we suggest that MLOs are more likely anaerobic mitochondria. © 2008 Australian Society for Parasitology Inc.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.ijpara.2008.06.001
dc.sourceScopus
dc.subjectBlastocystis hominis
dc.subjectCircular DNA molecule
dc.subjectIron-hydrogenase
dc.subjectMLOs
dc.typeArticle
dc.contributor.departmentMICROBIOLOGY
dc.description.doi10.1016/j.ijpara.2008.06.001
dc.description.sourcetitleInternational Journal for Parasitology
dc.description.volume38
dc.description.issue12
dc.description.page1377-1382
dc.description.codenIJPYB
dc.identifier.isiut000260286600004
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