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Title: The embryonic mouse gut tube as a model for analysis of epithelial polarity
Authors: Matsuyama, M.
Shimono, A. 
Keywords: Apicobasal (AB) polarity
Confocal microscope
Gut tube
Immunofluorescent staining
Oriented cell division
Issue Date: 2012
Citation: Matsuyama, M.,Shimono, A. (2012). The embryonic mouse gut tube as a model for analysis of epithelial polarity. Methods in Molecular Biology 839 : 229-237. ScholarBank@NUS Repository.
Abstract: Recent accumulating data indicate links between planer cell polarity (PCP) and apicobasal (AB) polarity in epithelial cells. PCP regulatory genes have been shown to be involved in the establishment of AB polarity in addition to regulating PCP. We have shown that the gut tube of the mouse embryo is a unique model system for the analysis of epithelial polarities, e.g., oriented cell division and AB polarity, with respect to the PCP pathway. The regulation of epithelial polarity by the PCP pathway might play an essential role in organ morphogenesis relating to physiological function. © 2012 Springer Science+Business Media, LLC.
Source Title: Methods in Molecular Biology
ISBN: 9781617795091
ISSN: 10643745
DOI: 10.1007/978-1-61779-510-7_18
Appears in Collections:Staff Publications

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