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https://doi.org/10.1080/03602530902741828
| Title: | Clinical pharmacology and pharmacogenetics of gemcitabine | Authors: | Wong, A. Soo, R.A. Yong, W.-P. Innocenti, F. |
Keywords: | Gemcitabine Pharmacogenetics Pharmacokinetics |
Issue Date: | May-2009 | Citation: | Wong, A., Soo, R.A., Yong, W.-P., Innocenti, F. (2009-05). Clinical pharmacology and pharmacogenetics of gemcitabine. Drug Metabolism Reviews 41 (2) : 77-88. ScholarBank@NUS Repository. https://doi.org/10.1080/03602530902741828 | Abstract: | Gemcitabine is a cytotoxic nucleoside analog, which is widely used in the treatment of malignancies. Interindividual differences in gemcitabine pharmacokinetics and pharmacodynamics have been demonstrated. Pharmacogenetic factors may account for a significant proportion of these differences. This review provides an update on the pharmacogenetics of gemcitabine and its influence on gemcitabine efficacy and toxicity. © 2009 Informa UK Ltd. | Source Title: | Drug Metabolism Reviews | URI: | http://scholarbank.nus.edu.sg/handle/10635/115536 | ISSN: | 03602532 | DOI: | 10.1080/03602530902741828 |
| Appears in Collections: | Staff Publications |
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