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Title: Clinical pharmacology and pharmacogenetics of gemcitabine
Authors: Wong, A.
Soo, R.A. 
Yong, W.-P. 
Innocenti, F.
Keywords: Gemcitabine
Issue Date: May-2009
Citation: Wong, A., Soo, R.A., Yong, W.-P., Innocenti, F. (2009-05). Clinical pharmacology and pharmacogenetics of gemcitabine. Drug Metabolism Reviews 41 (2) : 77-88. ScholarBank@NUS Repository.
Abstract: Gemcitabine is a cytotoxic nucleoside analog, which is widely used in the treatment of malignancies. Interindividual differences in gemcitabine pharmacokinetics and pharmacodynamics have been demonstrated. Pharmacogenetic factors may account for a significant proportion of these differences. This review provides an update on the pharmacogenetics of gemcitabine and its influence on gemcitabine efficacy and toxicity. © 2009 Informa UK Ltd.
Source Title: Drug Metabolism Reviews
ISSN: 03602532
DOI: 10.1080/03602530902741828
Appears in Collections:Staff Publications

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