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|Title:||Clinical pharmacology and pharmacogenetics of gemcitabine|
|Source:||Wong, A., Soo, R.A., Yong, W.-P., Innocenti, F. (2009-05). Clinical pharmacology and pharmacogenetics of gemcitabine. Drug Metabolism Reviews 41 (2) : 77-88. ScholarBank@NUS Repository. https://doi.org/10.1080/03602530902741828|
|Abstract:||Gemcitabine is a cytotoxic nucleoside analog, which is widely used in the treatment of malignancies. Interindividual differences in gemcitabine pharmacokinetics and pharmacodynamics have been demonstrated. Pharmacogenetic factors may account for a significant proportion of these differences. This review provides an update on the pharmacogenetics of gemcitabine and its influence on gemcitabine efficacy and toxicity. © 2009 Informa UK Ltd.|
|Source Title:||Drug Metabolism Reviews|
|Appears in Collections:||Staff Publications|
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