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Title: A study on occupational exposure to petrochemicals and smoking on seminal quality
Authors: Wang, S.-L.
Wang, X.-R.
Chia, S.-E. 
Shen, H.-M. 
Song, L.
Xing, H.-X.
Chen, H.-Y.
Ong, C.-N. 
Keywords: Combined effect
Cross-sectional study
Seminal parameters
Smoking habit
Issue Date: 2001
Citation: Wang, S.-L., Wang, X.-R., Chia, S.-E., Shen, H.-M., Song, L., Xing, H.-X., Chen, H.-Y., Ong, C.-N. (2001). A study on occupational exposure to petrochemicals and smoking on seminal quality. Journal of Andrology 22 (1) : 73-78. ScholarBank@NUS Repository.
Abstract: A cross-sectional study of 68 petrochemical workers (23 had never smoked [E/NS], 45 were current smokers [E/S]) and 130 subjects with no known history of exposure to petrochemicals (49 had never smoked [NE/NS], 81 were current smokers [NE/S]) was conducted to assess the effect of occupational exposure to petrochemicals and smoking on semen quality. In-person interviews revealed occupational history, smoking habit, and lifestyle. Semen parameters such as volume, viability, sperm forward progression rate, sperm density, and total sperm count were determined for all subjects. The results show that the E/NS workers had a lower sperm forward progression rate (P < .05) compared with controls (NE/NS). Individuals in the NE/S group showed a significant inverse relationship between years smoked and sperm density (r = -.24, P < .05). The data also revealed that cigarette smokers who had worked in a petrochemical plant had significantly poorer quality semen, including sperm density, total sperm count, and forward progression rate, compared with the control (NE/NS) group (P < .01). Furthermore, there was a significant inverse correlation between combined exposure and smoking years, and sperm density (r = -.28, P < .05). These findings suggest that occupational exposure to petrochemical compounds may aggravate the adverse effect that smoking has on semen quality.
Source Title: Journal of Andrology
ISSN: 01963635
Appears in Collections:Staff Publications

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