Neuropeptide gene expression in transgenic animals

Abstract

Transgenic animal techniques offer today's neuroscientist the ability to experimentally manipulate neurosecretory systems with a precision undreamt of by our predecessors. The range of techniques now available, building as it does on our growing knowledge of physiological systems at the inter- and intracellular level, allows us to critically define molecular lesions and ask about their consequences to the whole organism. Neuroscients should grasp the opportunities afforded by these recent developments.