Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pone.0054211
Title: TAZ Expression as a Prognostic Indicator in Colorectal Cancer
Authors: Yuen, H.-F.
McCrudden, C.M.
Huang, Y.-H.
Tham, J.M.
Zhang, X.
Zeng, Q. 
Zhang, S.-D.
Hong, W.J.
Issue Date: 29-Jan-2013
Citation: Yuen, H.-F., McCrudden, C.M., Huang, Y.-H., Tham, J.M., Zhang, X., Zeng, Q., Zhang, S.-D., Hong, W.J. (2013-01-29). TAZ Expression as a Prognostic Indicator in Colorectal Cancer. PLoS ONE 8 (1) : -. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0054211
Abstract: The Hippo pathway restricts the activity of transcriptional coactivators TAZ (WWTR1) and YAP. TAZ and YAP are reported to be overexpressed in various cancers, however, their prognostic significance in colorectal cancers remains unstudied. The expression levels of TAZ and YAP, and their downstream transcriptional targets, AXL and CTGF, were extracted from two independent colon cancer patient datasets available in the Gene Expression Omnibus database, totaling 522 patients. We found that mRNA expressions of both TAZ and YAP were positively correlated with those of AXL and CTGF (p
Source Title: PLoS ONE
URI: http://scholarbank.nus.edu.sg/handle/10635/112100
ISSN: 19326203
DOI: 10.1371/journal.pone.0054211
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