Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pone.0054211
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dc.titleTAZ Expression as a Prognostic Indicator in Colorectal Cancer
dc.contributor.authorYuen, H.-F.
dc.contributor.authorMcCrudden, C.M.
dc.contributor.authorHuang, Y.-H.
dc.contributor.authorTham, J.M.
dc.contributor.authorZhang, X.
dc.contributor.authorZeng, Q.
dc.contributor.authorZhang, S.-D.
dc.contributor.authorHong, W.J.
dc.date.accessioned2014-11-28T02:53:11Z
dc.date.available2014-11-28T02:53:11Z
dc.date.issued2013-01-29
dc.identifier.citationYuen, H.-F., McCrudden, C.M., Huang, Y.-H., Tham, J.M., Zhang, X., Zeng, Q., Zhang, S.-D., Hong, W.J. (2013-01-29). TAZ Expression as a Prognostic Indicator in Colorectal Cancer. PLoS ONE 8 (1) : -. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0054211
dc.identifier.issn19326203
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/112100
dc.description.abstractThe Hippo pathway restricts the activity of transcriptional coactivators TAZ (WWTR1) and YAP. TAZ and YAP are reported to be overexpressed in various cancers, however, their prognostic significance in colorectal cancers remains unstudied. The expression levels of TAZ and YAP, and their downstream transcriptional targets, AXL and CTGF, were extracted from two independent colon cancer patient datasets available in the Gene Expression Omnibus database, totaling 522 patients. We found that mRNA expressions of both TAZ and YAP were positively correlated with those of AXL and CTGF (p
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1371/journal.pone.0054211
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentINSTITUTE OF MOLECULAR & CELL BIOLOGY
dc.description.doi10.1371/journal.pone.0054211
dc.description.sourcetitlePLoS ONE
dc.description.volume8
dc.description.issue1
dc.description.page-
dc.identifier.isiut000314021500040
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