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https://doi.org/10.1016/S0040-4039(99)01050-3
| Title: | Solution-phase parallel oxazole synthesis with TosMIC | Authors: | Kulkarni, B.A. Ganesan, A. |
Keywords: | Combinatorial chemistry Isocyanides Oxazoles Supported reagents/reactions |
Issue Date: | Jul-1999 | Citation: | Kulkarni, B.A., Ganesan, A. (1999-07). Solution-phase parallel oxazole synthesis with TosMIC. Tetrahedron Letters 40 (30) : 5637-5638. ScholarBank@NUS Repository. https://doi.org/10.1016/S0040-4039(99)01050-3 | Abstract: | A quaternary ammonium hydroxide ion exchange resin catalyzes the reaction of p-tolylsulfonylmethyl isocyanide (TosMIC) with aromatic aldehydes to give 5-aryloxazoles. The base and the p-tolylsulfinic acid byproduct are removed by simple filtration, resulting in oxazoles in high yield and purity. | Source Title: | Tetrahedron Letters | URI: | http://scholarbank.nus.edu.sg/handle/10635/112080 | ISSN: | 00404039 | DOI: | 10.1016/S0040-4039(99)01050-3 |
| Appears in Collections: | Staff Publications |
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