Solid-phase C-acylation of active methylene compounds

Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0040-4039(98)00173-7

Title:	Solid-phase C-acylation of active methylene compounds
Authors:	Sim, M.M. Lee, C.L. Ganesan, A.
Issue Date:	9-Apr-1998
Citation:	Sim, M.M., Lee, C.L., Ganesan, A. (1998-04-09). Solid-phase C-acylation of active methylene compounds. Tetrahedron Letters 39 (15) : 2195-2198. ScholarBank@NUS Repository. https://doi.org/10.1016/S0040-4039(98)00173-7
Abstract:	Active methylene compounds were attached to the Wang resin by an ester linkage. C-acylation was achieved with a reactive species generated in sire by the combination of a carboxylic acid, diethyl phosphorocyanidate, and triethylamine. Cleavage from the resin with simultaneous decarboxylation gave the products in moderate to good yield.
Source Title:	Tetrahedron Letters
URI:	http://scholarbank.nus.edu.sg/handle/10635/112074
ISSN:	00404039
DOI:	10.1016/S0040-4039(98)00173-7
Appears in Collections:	Staff Publications

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