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Title: Solid-phase C-acylation of active methylene compounds
Authors: Sim, M.M. 
Lee, C.L.
Ganesan, A. 
Issue Date: 9-Apr-1998
Citation: Sim, M.M., Lee, C.L., Ganesan, A. (1998-04-09). Solid-phase C-acylation of active methylene compounds. Tetrahedron Letters 39 (15) : 2195-2198. ScholarBank@NUS Repository.
Abstract: Active methylene compounds were attached to the Wang resin by an ester linkage. C-acylation was achieved with a reactive species generated in sire by the combination of a carboxylic acid, diethyl phosphorocyanidate, and triethylamine. Cleavage from the resin with simultaneous decarboxylation gave the products in moderate to good yield.
Source Title: Tetrahedron Letters
ISSN: 00404039
DOI: 10.1016/S0040-4039(98)00173-7
Appears in Collections:Staff Publications

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