Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/111732
Title: Persistent low concentrations of diarrhetic shellfish toxins in green mussels Perna viridis from the Johor Strait, Singapore: First record of diarrhetic shellfish toxins from South-East Asia
Authors: Holmes, M.J. 
Teo, S.L.M. 
Lee, F.C. 
Khoo, H.W. 
Keywords: Diarrhetic Shellfish Poisoning
Dinoflagellate
Dinophysis caudata
Dinophysistoxin
Mass spectrometry
Okadaic acid
Perna viridis
Issue Date: 18-May-1999
Citation: Holmes, M.J.,Teo, S.L.M.,Lee, F.C.,Khoo, H.W. (1999-05-18). Persistent low concentrations of diarrhetic shellfish toxins in green mussels Perna viridis from the Johor Strait, Singapore: First record of diarrhetic shellfish toxins from South-East Asia. Marine Ecology Progress Series 181 : 257-268. ScholarBank@NUS Repository.
Abstract: Liquid chromatography-selected reaction monitoring mass spectrometry was used to identify and quantify Diarrhetic Shellfish Poisoning (DSP) toxins for the first time from tropical shellfish. Persistent, low concentrations of okadaic acid, 6 isomers of okadaic acid, and 5 isomers of dinophysistoxin-1 (DTX-1) were detected from green mussels Perna viridis from 3 sites in the Johor Strait, Singapore, between October 1995 and December 1997. Isomers of okadaic acid and DTX-1 generally occurred in higher concentrations than okadaic acid. The highest concentration of any single DSP toxin detected from Singapore shellfish was 97 ng g-1 mussel digestive tissue (wet weight) of an isomer of DTX-1 (DTX-1a). The maximum concentration of okadaic acid detected was 24 ng g-1 digestive tissue. These concentrations are well below the generally recommended limit for consumption of DSP toxins for humans (~1 μg toxin g-1 digestive tissue). Naturally contaminated mussels rapidly depurated okadaic acid when held in a laboratory aquarium; however, okadaic acid and some isomers of okadaic acid and DTX-1 could still be detected (
Source Title: Marine Ecology Progress Series
URI: http://scholarbank.nus.edu.sg/handle/10635/111732
ISSN: 01718630
Appears in Collections:Staff Publications

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