Please use this identifier to cite or link to this item: https://doi.org/10.1186/1477-7819-9-12
Title: Retroperitoneal liposarcomas: The experience of a tertiary Asian center
Authors: Lee, S.Y.
Goh, B.K.P.
Teo, M.C.C.
Chew, M.H.
Chow, P.K.H. 
Wong, W.K.
Ooi, L.L.P.J. 
Soo, K.C.
Issue Date: 1-Feb-2011
Citation: Lee, S.Y., Goh, B.K.P., Teo, M.C.C., Chew, M.H., Chow, P.K.H., Wong, W.K., Ooi, L.L.P.J., Soo, K.C. (2011-02-01). Retroperitoneal liposarcomas: The experience of a tertiary Asian center. World Journal of Surgical Oncology 9 : -. ScholarBank@NUS Repository. https://doi.org/10.1186/1477-7819-9-12
Abstract: Background: Liposarcoma is the single most common soft tissue sarcoma in the retroperitoneum.Materials and methods: A retrospective review of patients with primary retroperitoneal liposarcoma treated between June 1990 and June 2005 were conducted to evaluate the clinical results of resection for retroperitoneal liposarcomas (RPLS) and the prognostic factors for disease recurrence and patient survival in an Asian population.Results: Twenty-one patients operated on for curative intent (12 Males, 9 Females; mean age: 52.4 years) were evaluated. Of these, 13 presented with tumors that were well differentiated (61.9%), 4 (19.0%) with myxoid/round cell, 3 (14.3%) with dedifferentiated and 1(4.8%) with pleomorphic morphology. The median tumor burden was 36 cm (9-83). Median follow-up time was 62 months. There was no peri-operative mortality and morbidity occurred in 6(28.6%) patients. Surgical margins were involved in 10(47.6%) patients. Resection of contiguous organs was required in 15(71.4%) to achieve gross surgical margins. Eleven out of the 21(52%) of the patients had recurrence of the tumor. Median disease-free survival was 19 months and the overall 3- and 5-year survival rate was 87% and 49% respectively.Conclusion: An aggressive surgical approach in both primary and recurrent RPLS in our institution is associated with 3- and 5-year survival rate of 87% and 49% respectively. Contiguous organ resection is often required to achieve local control. © 2011 Lee et al; licensee BioMed Central Ltd.
Source Title: World Journal of Surgical Oncology
URI: http://scholarbank.nus.edu.sg/handle/10635/110254
ISSN: 14777819
DOI: 10.1186/1477-7819-9-12
Appears in Collections:Staff Publications
Elements

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
2011-retroperitoneal_liposarcomas_experience_tertiary_Asian-pub.pdf346.98 kBAdobe PDF

OPEN

PublishedView/Download

SCOPUSTM   
Citations

32
checked on Feb 21, 2020

WEB OF SCIENCETM
Citations

29
checked on Feb 13, 2020

Page view(s)

118
checked on Feb 22, 2020

Download(s)

2
checked on Feb 22, 2020

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.