Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1445-2197.2007.04176.x
Title: Significance of tumour volume measurements in tongue cancer: A novel role in staging
Authors: Chew, M.H.
Khoo, J.B.K.
Chong, V.F.H.
Tai, B.C. 
Soo, K.C.
Lim, D.T.H.
Keywords: MRI
Staging
Tongue cancer
Tumour volume
Issue Date: Aug-2007
Citation: Chew, M.H., Khoo, J.B.K., Chong, V.F.H., Tai, B.C., Soo, K.C., Lim, D.T.H. (2007-08). Significance of tumour volume measurements in tongue cancer: A novel role in staging. ANZ Journal of Surgery 77 (8) : 632-637. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1445-2197.2007.04176.x
Abstract: Background: Tongue cancers are staged by the American Joint Committee on Cancer and the Union Internationale Contre le Cancer TNM staging systems. Cancer, however, evolves in a 3-D plane. Hence, using the largest tumour diameter will not reflect total cancer volume. We aim to evaluate the use of tongue cancer tumour volume (Tv) as a prognostic predictor of disease recurrence and survival. Methods: The study is a retrospective analysis of patients in Singapore General Hospital who underwent complete resection for histologically proven tongue carcinoma from 2000 to 2002. The Tv was measured on staging T2-weighted magnetic resonance imaging datasets by semiautomated methods. Results: Seventeen patients with a median follow-up duration of 57.9 months were studied. A wide range of volumes was noted in each T stage. The median time to relapse was 8.6 months for those with Tv ≥ 13 cc but was not achieved for those with Tv < 13 cc. The hazard ratio comparing Tv ≥13 cc versus
Source Title: ANZ Journal of Surgery
URI: http://scholarbank.nus.edu.sg/handle/10635/109652
ISSN: 14451433
DOI: 10.1111/j.1445-2197.2007.04176.x
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