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https://doi.org/10.1111/j.1445-2197.2007.04176.x
Title: | Significance of tumour volume measurements in tongue cancer: A novel role in staging | Authors: | Chew, M.H. Khoo, J.B.K. Chong, V.F.H. Tai, B.C. Soo, K.C. Lim, D.T.H. |
Keywords: | MRI Staging Tongue cancer Tumour volume |
Issue Date: | Aug-2007 | Citation: | Chew, M.H., Khoo, J.B.K., Chong, V.F.H., Tai, B.C., Soo, K.C., Lim, D.T.H. (2007-08). Significance of tumour volume measurements in tongue cancer: A novel role in staging. ANZ Journal of Surgery 77 (8) : 632-637. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1445-2197.2007.04176.x | Abstract: | Background: Tongue cancers are staged by the American Joint Committee on Cancer and the Union Internationale Contre le Cancer TNM staging systems. Cancer, however, evolves in a 3-D plane. Hence, using the largest tumour diameter will not reflect total cancer volume. We aim to evaluate the use of tongue cancer tumour volume (Tv) as a prognostic predictor of disease recurrence and survival. Methods: The study is a retrospective analysis of patients in Singapore General Hospital who underwent complete resection for histologically proven tongue carcinoma from 2000 to 2002. The Tv was measured on staging T2-weighted magnetic resonance imaging datasets by semiautomated methods. Results: Seventeen patients with a median follow-up duration of 57.9 months were studied. A wide range of volumes was noted in each T stage. The median time to relapse was 8.6 months for those with Tv ≥ 13 cc but was not achieved for those with Tv < 13 cc. The hazard ratio comparing Tv ≥13 cc versus | Source Title: | ANZ Journal of Surgery | URI: | http://scholarbank.nus.edu.sg/handle/10635/109652 | ISSN: | 14451433 | DOI: | 10.1111/j.1445-2197.2007.04176.x |
Appears in Collections: | Staff Publications |
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