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https://doi.org/10.3109/02713683.2012.754046
Title: | Retinal venular calibre is increased in patients with autoimmune rheumatic disease: A case-control study | Authors: | Okada, M. Wong, T.Y. Kawasaki, R. Baharuddin, N.B. Colville, D. Buchanan, R. Savige, J. |
Keywords: | Autoimmune rheumatic disease Microvasculature Retinal vascular caliber Rheumatoid arthritis Systemic inflammation |
Issue Date: | Jun-2013 | Citation: | Okada, M., Wong, T.Y., Kawasaki, R., Baharuddin, N.B., Colville, D., Buchanan, R., Savige, J. (2013-06). Retinal venular calibre is increased in patients with autoimmune rheumatic disease: A case-control study. Current Eye Research 38 (6) : 685-690. ScholarBank@NUS Repository. https://doi.org/10.3109/02713683.2012.754046 | Abstract: | Aim: To examine retinal vessel calibre in autoimmune rheumatic disease. Materials and methods: Patients with autoimmune rheumatic disease were recruited from a Rheumatology clinic. Retinal vessel calibre was measured from fundus photographs, and summarised as the central retinal artery and vein equivalents (CRAE and CRVE) using a semi-automated computer-assisted method. Results: The 124 patients studied had rheumatoid arthritis (n=76, 61%), systemic lupus erythematosus (n=17, 14%), psoriatic arthritis (n=11, 9%) or another rheumatological disease (n=20, 16%). Retinal venular calibre was increased in patients with autoimmune rheumatic disease (+11.6μm, 95% Confidence interval [CI] 3.8-19.3, p=0.01) compared with other hospital patients, after adjusting for baseline differences. This increase was also present in the subgroup with rheumatoid arthritis (p=0.01). Patients with a rheumatic disease and elevated C-reactive protein (CRP) levels had wider retinal venules than those with a lower CRP (mean CRVE: 247.8±28.0 versus 216.6±25.3, p | Source Title: | Current Eye Research | URI: | http://scholarbank.nus.edu.sg/handle/10635/108526 | ISSN: | 02713683 | DOI: | 10.3109/02713683.2012.754046 |
Appears in Collections: | Staff Publications |
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