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Title: Procedure-related myonecrosis after bare and drug-eluting stent implantation
Authors: Lee, C.-H.
Tse, H.-F.
Tai, B.-C. 
Chen, Z. 
Chan, M.Y.
Tan, H.-C.
Keywords: Angioplasty
Coronary Artery Disease
Drug-Eluting Stents
Myocardial Infarction
Percutaneous Coronary
Issue Date: Jun-2010
Citation: Lee, C.-H.,Tse, H.-F.,Tai, B.-C.,Chen, Z.,Chan, M.Y.,Tan, H.-C. (2010-06). Procedure-related myonecrosis after bare and drug-eluting stent implantation. Asian Cardiovascular and Thoracic Annals 18 (3) : 272-278. ScholarBank@NUS Repository.
Abstract: We sought to compare the incidence of myonecrosis after elective implantation of bare metal stents with that of drug-eluting stents. The data of stable patients who were treated with stenting in a single native coronary artery were analyzed retrospectively. The stents used were bare metal in 119, sirolimus-eluting (Cypher Select Plus) in 119 patients, paclitaxel-eluting (Taxus Liberté) in 120, zotarolimus-eluting (Endeavor Sprint) in 122, and everolimus-eluting (Xience V) in 72. Endpoints included post-procedural myonecrosis (any elevation of creatine kinase-MB), myocardial infarction (creatine kinase-MB >3 times the upper limit of normal), and large myocardial infarction (creatine kinase-MB >5 times the upper limit of normal). The incidences of myonecrosis (16.7%-18.9%), myocardial infarction (3.3%-8.4%), and large myocardial infarction (1.7%-5.6%) were not significantly different among stent types. At the 30-day follow-up, there were 2 deaths in patients who had Taxus Liberté stents, one death each in those with Xience V and bare metal stents, and no cases of stroke or target vessel revascularization. In this study, bare metal stents and the 4 drug-eluting stents were associated with similar low incidences of myonecrosis, myocardial infarction, and large myocardial infarction. © 2010 SAGE Publications.
Source Title: Asian Cardiovascular and Thoracic Annals
ISSN: 02184923
DOI: 10.1177/0218492310368732
Appears in Collections:Staff Publications

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