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Title: Novel anterior-chamber angle measurements by high-definition optical coherence tomography using the Schwalbe line as the landmark
Authors: Cheung, C.Y.
Zheng, C.
Ho, C.-L.
Tun, T.A.
Kumar, R.S.
El Sayyad, F.
Wong, T.Y. 
Aung, T.
Issue Date: Jul-2011
Citation: Cheung, C.Y., Zheng, C., Ho, C.-L., Tun, T.A., Kumar, R.S., El Sayyad, F., Wong, T.Y., Aung, T. (2011-07). Novel anterior-chamber angle measurements by high-definition optical coherence tomography using the Schwalbe line as the landmark. British Journal of Ophthalmology 95 (7) : 955-959. ScholarBank@NUS Repository.
Abstract: Objective: To propose the Schwalbe line (SL) as a new anatomical landmark, independent of the scleral spur (SS) location, for assessing anterior chamber angle (ACA) width quantitatively with high-definition optical coherence tomography (HD-OCT). Methods: Study subjects underwent dark-room gonioscopy and HD-OCT in one randomly selected eye. The authors developed a computer-aided program to define two new quantitative parameters for assessing ACA width: Schwalbe line-angle opening distance (SL-AOD) measured at the SL, and Schwalbe line-trabecular-iris space area (SL-TISA) measured 500 μm from the SL. The associations between SL parameters, SS parameters and gonioscopic grading were evaluated. Results: Seventy-three (47 females, 26 males) subjects were recruited, the majority of whom were Chinese (89%). The authors excluded 29 images (19.9%) owing to poor image quality, leaving 117 HD-OCT images (65 nasal, 52 temporal) for analysis. SL and SS could be identified in 95% and 85% of quadrants respectively (p=0.035). SL-AOD and SL-TISA were significantly correlated with SS parameters (all r≥0.85) and gonioscopic grading (all r≥0.69). In eyes with closed angles (n=36), SL parameters showed strong correlations with gonioscopic grading (r ranged from 0.43 to 0.44). Conclusions: Novel angle parameters, based on SL as a landmark, may be useful to quantify ACA width and to assess for risk of angle closure.
Source Title: British Journal of Ophthalmology
ISSN: 00071161
DOI: 10.1136/bjo.2010.189217
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