Alternative splicing of SMADs in differentiation and tissue homeostasis

Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1440-169X.2009.01163.x

Title:	Alternative splicing of SMADs in differentiation and tissue homeostasis
Authors:	Tao, S. Sampath, K.
Keywords:	RNA splicing SMADs TGF-β/SMAD signalling Tissue homeostasis
Issue Date:	May-2010
Citation:	Tao, S., Sampath, K. (2010-05). Alternative splicing of SMADs in differentiation and tissue homeostasis. Development Growth and Differentiation 52 (4) : 335-342. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1440-169X.2009.01163.x
Abstract:	Tissue-specific alternate splicing is an important means of regulating gene expression during development. The effector proteins for the transforming growth factor-β signaling pathway, the SMADs, encode distinct isoforms generated via alternate splicing, which appear to have distinct tissue-specific expression profiles and functions. Here, we discuss the roles of various SMAD isoforms, and the consequences of mis-regulation of SMAD splicing in development and tissue homeostasis. © 2010 Japanese Society of Developmental Biologists.
Source Title:	Development Growth and Differentiation
URI:	http://scholarbank.nus.edu.sg/handle/10635/102401
ISSN:	00121592
DOI:	10.1111/j.1440-169X.2009.01163.x
Appears in Collections:	Staff Publications

There are no files associated with this item.

Check