Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0048-9697(98)00061-8
Title: Effects of mercuric chloride and sodium selenite on some immune responses of blue gourami, Trichogaster trichopterus (Pallus)
Authors: Low, K.W. 
Sin, Y.M. 
Keywords: Blue gourami
Immunotoxicology
Mercuric chloride
Sodium selenite
Issue Date: 18-Jun-1998
Citation: Low, K.W., Sin, Y.M. (1998-06-18). Effects of mercuric chloride and sodium selenite on some immune responses of blue gourami, Trichogaster trichopterus (Pallus). Science of the Total Environment 214 (1-3) : 153-164. ScholarBank@NUS Repository. https://doi.org/10.1016/S0048-9697(98)00061-8
Abstract: The immunotoxicological effects of mercuric chloride and sodium selenite on blue gourami were studied. Some immune responses ranging from non-specific to specific were investigated. These include tissue lysozyme activity, kidney lymphocyte proliferation and plasma agglutinating antibody titre against bacteria. After 2 weeks of chronic exposure, 0.09 mg/l of Hg2+ alone induced a significant increase of kidney lysozyme activity of 4196.3 ± 1171.0 U/g, but it decreased to 1577.4 ± 902.4 U/g when exposed simultaneously to equiconcentration of selenium. Plasma lysozyme activity was also increased by co-administration of Hg2+ and SeO3/2-. The level of plasma agglutinating antibody against Aeromonas hydrophila L37 was lowered in the chemical-treated fish. This indicates that the fish immunity was impaired by action of mercury and selenium. However, the in vitro lymphocyte proliferation test shows that mercury concentration lower than 0.045 mg/l Hg2+ enhanced the mitotic rate of kidney lymphocytes by approximately 30%. A high concentration of mercury caused irreversible damaging effects on con A-induced lymphoblastogenesis. In contrast, the inhibitory effect of low concentrations of mercury could be removed by washing. On the other hand, selenium showed a suppressire effect on the lymphocyte proliferation even at 0.5 rag/l.
Source Title: Science of the Total Environment
URI: http://scholarbank.nus.edu.sg/handle/10635/100550
ISSN: 00489697
DOI: 10.1016/S0048-9697(98)00061-8
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

29
checked on Sep 24, 2021

WEB OF SCIENCETM
Citations

26
checked on Sep 16, 2021

Page view(s)

86
checked on Sep 23, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.