Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/100448
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dc.titleDexamethasone receptors and their distribution in the brain of the red tilapia
dc.contributor.authorChen, K.M.
dc.contributor.authorChan, W.K.
dc.contributor.authorMunro, A.D.
dc.date.accessioned2014-10-27T08:25:58Z
dc.date.available2014-10-27T08:25:58Z
dc.date.issued1997
dc.identifier.citationChen, K.M., Chan, W.K., Munro, A.D. (1997). Dexamethasone receptors and their distribution in the brain of the red tilapia. Fish Physiology and Biochemistry 16 (3) : 171-179. ScholarBank@NUS Repository.
dc.identifier.issn09201742
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/100448
dc.description.abstractCytosolic extracts of liver and brain showed specific, saturable binding with [3H]dexamethasone: Scatchard plots were linear. Cortisol and 11-deoxycortisol acted as competitors, whilst 17α,20α-dihydroxy-4-pregnen-3-one was relatively much less effective. There was a four-fold range of differences in specific binding capacity between dissected brain regions, the order being telencephalon > hypothalamus > rhombencephalon > optic tectum ≈ (thalamus + tegmentum + torus semicircularis) when Nmax was calculated in terms of DNA content. There was no evidence for any binding of [3H]dexamethasone with membrane fractions.
dc.sourceScopus
dc.subjectBrain
dc.subjectCortisol receptors
dc.subjectDexamethasone-binding
dc.subjectTilapia
dc.typeArticle
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.sourcetitleFish Physiology and Biochemistry
dc.description.volume16
dc.description.issue3
dc.description.page171-179
dc.description.codenFPBIE
dc.identifier.isiutNOT_IN_WOS
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