Full Name
Sir David Lane
Main Affiliation
 
 
Email
mdcsdl@nus.edu.sg
 

Publications

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Department:  BIOLOGY (NU)

Results 1-12 of 12 (Search time: 0.014 seconds).

Issue DateTitleAuthor(s)
12017A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53Wong, J.H; Alfatah, M; Sin, M.F; Sim, H.M ; Verma, C.S ; Lane, D.P ; Arumugam, P 
22016Avoiding drug resistance through extended drug target interfaces: A case for stapled peptidesWei, S.J; Chee, S; Yurlova, L; Lane, D ; Verma, C ; Brown, C; Ghadessy, F
32016Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand DesignTan, Y.S; Reeks, J; Brown, C.J; Thean, D; Ferrer Gago, F.J; Yuen, T.Y; Goh, E.T.L; Lee, X.E.C; Jennings, C.E; Joseph, T.L; Lakshminarayanan, R ; Lane, D.P ; Noble, M.E.M; Verma, C.S 
42017Characterizing the conformational landscape of MDM2-binding p53 peptides using Molecular Dynamics simulationsYadahalli, S; Li, J ; Lane, D.P ; Gosavi, S; Verma, C.S 
52010Differences in the transactivation domains of p53 family members: A computational studyMavinahalli, J.N; Madhumalar, A; Beuerman, R.W ; Lane, D.P ; Verma, C 
62016Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerensSiau, J.W; Coffill, C.R; Zhang, W.V; Tan, Y.S; Hundt, J; Lane, D ; Verma, C ; Ghadessy, F
72014High Mdm4 levels suppress p53 activity and enhance its half-life in acute myeloid leukaemiaTan, B.X; Khoo, K.H; Lim, T.M ; Lane, D.P 
82016Long range recognition and selection in IDPs: The interactions of the C-terminus of p53Kannan, S; Lane, D.P ; Verma, C.S 
93-Dec-2009Modulation of p53 binding to MDM2: Computational studies reveal important roles of Tyr100Dastidar, S.G.; Lane, D.P. ; Verma, C.S. 
102017Role of the N-terminal lid in regulating the interaction of phosphorylated MDMX with p53Chan, J.V; Koh, D.X.P; Liu, Y; Joseph, T.L; Lane, D.P ; Verma, C.S ; Tan, Y.S
112014Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2Chee S.M.Q.; Wongsantichon J.; Soo Tng Q.; Robinson R. ; Joseph T.L.; Verma C. ; Lane D.P. ; Brown C.J.; Ghadessy F.J.
1229-Apr-2020Targeting codon 158 p53-mutant cancers via the induction of p53 acetylationKong, Li Ren ; Ong, Richard Weijie; Tan, Tuan Zea ; Salleh, Nur Afiqah Binte Mohamed ; Thangavelu, Matan; Chan, Jane Vin; Koh, Lie Yong Judice; Periyasamy, Giridharan; Lau, Jieying Amelia ; Le, Thi Bich Uyen; Wang, Lingzhi ; Lee, Miyoung; Kannan, Srinivasaraghavan; Verma, Chandra S ; Lim, Chwee Ming ; Chng, Wee Joo ; Lane, David P ; Venkitaraman, Ashok ; Hung, Huynh The; Cheok, Chit Fang ; Goh, Boon Cher