1. ScholarBank@NUS

Sim Tiow Suan

rp04521

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Full Name
Sim Tiow Suan
(not current staff)
Variants
Tiow-Suan, S.
Sim, T.-W.
Sim, T.S.
Sim, T.-S.
Suan, S.T..
 
Main Affiliation
 
Faculty
 
Email
micsimts@nus.edu.sg
 

Publications

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Type:  Article
Subject:  Isopenicillin N synthase

Results 1-19 of 19 (Search time: 0.004 seconds).

Issue DateTitleAuthor(s)
11998Analysis of a conserved arginine R281L in catalysis in Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
21998Analysis of glutamines in catalysis in Cephalosporium acremonium isopenicillin N synthase by site-directed mutagenesisLoke, P. ; Tiow Suan Sim 
31998Catalytic activity in cephalosporium acremonium isopenicillin N synthase does not involve glutamine-234Loke, P. ; Tiow Suan Sim 
42001Construction of Streptomyces jumonjinensis isopenicillin N synthase double mutants, Ser119Ala/Glu120Gly and Thr308Ala/Thr309Val, overcomes insoluble expression in Escherichia coliWong, E.; Sim, J.; Sim, T.-S. 
51-Dec-1997Functional analysis of a conserved aspartate D218 in Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, J.; Sim, T.-S. 
61999Glutamine-230 influences enzyme solubility but not catalysis in Streptomyces clavuligerus isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
71994Histidine-272 of isopenicillin N synthase of Cephalosporium acremonium, which is possibly involved in iron binding, is essential for its catalytic activityTiow-Suan, S. ; Tan, D.S.H. 
81998Involvement of a third histidine in the ferrous active site of isopenicillin N synthase of Cephalosporium acremonium repudiated by recombinant double histidine mutantsTan, D.S.H. ; Ang, S.G. ; Sim, T.S. 
92001Mutation of N304 to leucine in Streptomyces clavuligerus deacetoxycephalosporin C synthase creates an enzyme with increased penicillin analogue conversionChin, H.S.; Sim, J.; Sim, T.S. 
102001Mutational analysis of conserved glycines 42 and 256 in Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
112001Mutational analysis of conserved glycines 42 and 256 in Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Tiow Suan Sim 
122000Mutational analysis of tyrosine-191 in the catalysis of Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
132000Mutational analysis of tyrosine-191 in the catalysis of Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-W. 
1415-Aug-1998Mutational evidence for the role of serine-283 in Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
152000PCR cloning, heterologous expression, and characterization of isopenicillin N synthase from Streptomyces lipmanii NRRL 3584Loke, P. ; Ng, C.P.; Sim, T.-S. 
162000PCR cloning, heterologous expression, and characterization of isopenicillin N synthase from Streptomyces lipmanii NRRL 3584Loke, P. ; Ng, C.P.; Sim, T.-S. 
1715-Oct-1999Site-directed mutagenesis of arginine-89 supports the role of its guanidino side-chain in substrate binding by Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
181999Site-directed mutagenesis of arginine-89 supports the role of its guanidino side-chain in substrate binding by Cephalosporium acremonium isopenicillin N synthaseLoke, P. ; Sim, T.-S. 
192001The invariant F283 and its strategic position in the hydrophobic cleft of streptomyces jumonjinensis isopenicillin N synthase active site are functionally importantWong, E.; Sim, J. ; Sim, T.-S.