Please use this identifier to cite or link to this item: https://doi.org/10.1021/ja064305a
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dc.titleCompaction dynamics of single DNA molecules under tension
dc.contributor.authorFu, W.-B.
dc.contributor.authorWang, X.-L.
dc.contributor.authorZhang, X.-H.
dc.contributor.authorRan, S.-Y.
dc.contributor.authorYan, J.
dc.contributor.authorLi, M.
dc.date.accessioned2014-10-16T09:18:38Z
dc.date.available2014-10-16T09:18:38Z
dc.date.issued2006-11-29
dc.identifier.citationFu, W.-B., Wang, X.-L., Zhang, X.-H., Ran, S.-Y., Yan, J., Li, M. (2006-11-29). Compaction dynamics of single DNA molecules under tension. Journal of the American Chemical Society 128 (47) : 15040-15041. ScholarBank@NUS Repository. https://doi.org/10.1021/ja064305a
dc.identifier.issn00027863
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/96027
dc.description.abstractUsing transverse magnetic tweezers, we studied the dynamics of DNA compaction induced by hexaammine cobalt chloride under constant forces. Discontinuous DNA compaction events were found for forces ranging from 0.5 to 1.7 pN, with ∼270 nm DNA adsorbed in each compaction event. Forces larger than 6 pN were found able to unravel the toroid in a similar intermittent stepwise manner. The observations indicate that the folding/unfolding events are transitions between two metastable structural states which are separated by a tension-dependent energy barrier. Analysis of the waiting time revealed that the degree of the package ordering of DNA in a toroid depends on the compaction kinetics. Copyright © 2006 American Chemical Society.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1021/ja064305a
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentPHYSICS
dc.description.doi10.1021/ja064305a
dc.description.sourcetitleJournal of the American Chemical Society
dc.description.volume128
dc.description.issue47
dc.description.page15040-15041
dc.description.codenJACSA
dc.identifier.isiut000242216100003
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