Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.nimb.2009.03.063
DC FieldValue
dc.titleAngular and lateral spreading of ion beams in biomedical nuclear microscopy
dc.contributor.authorWhitlow, H.J.
dc.contributor.authorRen, M.
dc.contributor.authorvan Kan, J.A.
dc.contributor.authorOsipowicz, T.
dc.contributor.authorWatt, F.
dc.date.accessioned2014-10-16T09:15:48Z
dc.date.available2014-10-16T09:15:48Z
dc.date.issued2009-06-15
dc.identifier.citationWhitlow, H.J., Ren, M., van Kan, J.A., Osipowicz, T., Watt, F. (2009-06-15). Angular and lateral spreading of ion beams in biomedical nuclear microscopy. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms 267 (12-13) : 2153-2156. ScholarBank@NUS Repository. https://doi.org/10.1016/j.nimb.2009.03.063
dc.identifier.issn0168583X
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/95787
dc.description.abstractNuclear scattering from target atoms gives rise to a spatial broadening of energetic ion beams penetrating matter. The spatial broadening of the ion beam presents an ultimate limit to the resolving power that can be achieved in nuclear microscopy methods. The pressing of the attainable resolution limit in biomedical nuclear microscopy to dimensions approaching 10 nm, or so, implies the fundamental limitation from ion-target scattering will become increasingly significant. This effect has been investigated by a combined analytical and numerical computational approach to determine the extent and how single and multiple scattering processes limit the resolution for analysis with 2 MeV 4He and 1H ions of realistic biomedical samples. The cases studied were direct-Scanning Transmission Ion Microscopy (direct-STIM), Particle Induced X-ray Emission (PIXE) studies of 20 μm tissue sections and in vivo single-ion irradiation of cells. © 2009 Elsevier B.V. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.nimb.2009.03.063
dc.sourceScopus
dc.subjectBiomedical imaging
dc.subjectMultiple scattering
dc.subjectNuclear microscopy
dc.subjectPIXE
dc.subjectSTIM
dc.typeArticle
dc.contributor.departmentPHYSICS
dc.description.doi10.1016/j.nimb.2009.03.063
dc.description.sourcetitleNuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
dc.description.volume267
dc.description.issue12-13
dc.description.page2153-2156
dc.description.codenNIMBE
dc.identifier.isiut000267910500038
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