Please use this identifier to cite or link to this item: https://doi.org/10.1088/0031-9155/51/11/012
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dc.titleA biphasic parameter estimation method for quantitative analysis of dynamic renal scintigraphic data
dc.contributor.authorKoh, T.S.
dc.contributor.authorZhang, J.L.
dc.contributor.authorOng, C.K.
dc.contributor.authorShuter, B.
dc.date.accessioned2014-10-16T09:13:37Z
dc.date.available2014-10-16T09:13:37Z
dc.date.issued2006-06-07
dc.identifier.citationKoh, T.S., Zhang, J.L., Ong, C.K., Shuter, B. (2006-06-07). A biphasic parameter estimation method for quantitative analysis of dynamic renal scintigraphic data. Physics in Medicine and Biology 51 (11) : 2857-2870. ScholarBank@NUS Repository. https://doi.org/10.1088/0031-9155/51/11/012
dc.identifier.issn00319155
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/95601
dc.description.abstractDynamic renal scintigraphy is an established method in nuclear medicine, commonly used for the assessment of renal function. In this paper, a biphasic model fitting method is proposed for simultaneous estimation of both vascular and parenchymal parameters from renal scintigraphic data. These parameters include the renal plasma flow, vascular and parenchymal mean transit times, and the glomerular extraction rate. Monte Carlo simulation was used to evaluate the stability and confidence of the parameter estimates obtained by the proposed biphasic method, before applying the method on actual patient study cases to compare with the conventional fitting approach and other established renal indices. The various parameter estimates obtained using the proposed method were found to be consistent with the respective pathologies of the study cases. The renal plasma flow and extraction rate estimated by the proposed method were in good agreement with those previously obtained using dynamic computed tomography and magnetic resonance imaging. © 2006 IOP Publishing Ltd.
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentPHYSICS
dc.description.doi10.1088/0031-9155/51/11/012
dc.description.sourcetitlePhysics in Medicine and Biology
dc.description.volume51
dc.description.issue11
dc.description.page2857-2870
dc.description.codenPHMBA
dc.identifier.isiut000238924200012
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