Please use this identifier to cite or link to this item:
|Title:||Suppression of epimerization due to selectivity leakage: An application towards the total synthesis of (-)-centrolobine||Authors:||Lee, C.-H.A.
|Issue Date:||6-Mar-2006||Citation:||Lee, C.-H.A., Loh, T.-P. (2006-03-06). Suppression of epimerization due to selectivity leakage: An application towards the total synthesis of (-)-centrolobine. Tetrahedron Letters 47 (10) : 1641-1644. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2005.12.108||Abstract:||An InCl3-mediated Prins cyclization of homoallylic alcohols with aldehydes has been established. The enantioselectivities of the trisubstituted tetrahydropyrans are almost retained through the suppression of epimerization. The synthetic value of this protocol is demonstrated by the total synthesis of (-)-centrolobine. © 2006 Elsevier Ltd. All rights reserved.||Source Title:||Tetrahedron Letters||URI:||http://scholarbank.nus.edu.sg/handle/10635/94971||ISSN:||00404039||DOI:||10.1016/j.tetlet.2005.12.108|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jul 10, 2020
WEB OF SCIENCETM
checked on Jul 2, 2020
checked on Jun 27, 2020
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.