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| Title: | A highly stereoselective synthesis of β-trifluoromethylated homoallylic alcohols in water | Authors: | Loh, T.-P. Li, X.-R. |
Keywords: | aldehydes allylation fluorine indium tin |
Issue Date: | 1997 | Citation: | Loh, T.-P.,Li, X.-R. (1997). A highly stereoselective synthesis of β-trifluoromethylated homoallylic alcohols in water. Angewandte Chemie - International Edition in English 36 (9) : 980-982. ScholarBank@NUS Repository. | Abstract: | A tin-mediated, indium trichloride promoted allylation reaction provided β-trifluoromethylated homoallylic alcohols, the building blocks of biologically active substances, in high yields and excellent stereoselectivity. Since the syntheses can be carried out in water, the reactive OH groups do not need to be protected, and even compounds that are insoluble in organic solvents can be used. | Source Title: | Angewandte Chemie - International Edition in English | URI: | http://scholarbank.nus.edu.sg/handle/10635/92948 | ISSN: | 05700833 |
| Appears in Collections: | Staff Publications |
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