Please use this identifier to cite or link to this item:
Title: Future directions in lamellar corneal transplantation
Authors: Tan, D.T.H. 
Mehta, J.S.
Keywords: Anterior lamellar graft
Big bubble
Endothelial transplant
Femtosecond laser
Penetrating keratoplasty
Posterior lamellar keratoplasty
Issue Date: Oct-2007
Citation: Tan, D.T.H., Mehta, J.S. (2007-10). Future directions in lamellar corneal transplantation. Cornea 26 (SUPPL. 1) : S21-S28. ScholarBank@NUS Repository.
Abstract: The concept of lamellar keratoplasty (LK) is that of targeted lamellar replacement of corneal tissue while retaining normal cornea. It involves replacing either anterior stroma [anterior lamellar keratoplasty (ALK)] or posterior replacement of deep stromal and endothelial layers [posterior lamellar keratoplasty (PLK) or endothelial keratoplasty]. Despite the distinct advantages of ALK surgery, penetrating keratoplasty (PK) remains the most common procedure-largely because lamellar surgery is more technically demanding and time consuming, and interface irregularity arising from manual lamellar dissection often results in suboptimal visual outcomes. Recent improvements of surgical technique and advances in instrumentation such as microkeratome- assisted lamellar transplantation have contributed to improved visual quality with LK surgery. Long-term graft survival rates and endothelial cell counts after PK continue to drop for many years after surgery, clearly showing the disadvantage of unnecessary replacement of healthy endothelium in anterior-stromal disorders. The aim of this review is to evaluate the shifting emphasis from penetrating to lamellar forms of corneal transplantation and to highlight some future directions in lamellar surgery including new techniques in both ALK and PLK and the use of microkeratomes and femtosecond lasers to enhance outcomes. © 2007 Lippincott Williams & Wilkins, Inc.
Source Title: Cornea
ISSN: 02773740
DOI: 10.1097/ICO.0b013e31812f685c
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.