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Please use this identifier to cite or link to this item: https://doi.org/10.1007/978-3-540-92841-6_370
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dc.titleTissue Transglutaminase as a Biological Tissue Glue
dc.contributor.authorPanengad, P.P.
dc.contributor.authorZeugolis, D.I.
dc.contributor.authorRaghunath, M.
dc.date.accessioned2014-10-08T09:50:36Z
dc.date.available2014-10-08T09:50:36Z
dc.date.issued2009
dc.identifier.citationPanengad, P.P.,Zeugolis, D.I.,Raghunath, M. (2009). Tissue Transglutaminase as a Biological Tissue Glue. IFMBE Proceedings 23 : 1496-1498. ScholarBank@NUS Repository. <a href="https://doi.org/10.1007/978-3-540-92841-6_370" target="_blank">https://doi.org/10.1007/978-3-540-92841-6_370</a>
dc.identifier.isbn9783540928409
dc.identifier.issn16800737
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/88367
dc.description.abstractSurgeons have long sought an efficient biological method of wound repair that requires little time and minimizes discomfort for their patients, yet produces a good cosmetic outcome. Our aim is to develop a biological tissue glue based on the extracellular matrix stabilizing enzyme transglutaminase 2 to covalently bond tissue layers to promote suture-less closure of surgical wounds. We used human skin tissue as a model to test our hypothesis. Human skin samples were studied for endogenous transglutaminase activity and probed for target structures for commercial enzyme using standardized histochemistry. Tissue bonding between two skin sections was monitored under phase contrast microscopy.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1007/978-3-540-92841-6_370
dc.sourceScopus
dc.subjectbiological tissue glue
dc.subjecthistochemistry
dc.subjectskin
dc.subjectTransglutaminase
dc.typeConference Paper
dc.contributor.departmentBIOENGINEERING
dc.description.doi10.1007/978-3-540-92841-6_370
dc.description.sourcetitleIFMBE Proceedings
dc.description.volume23
dc.description.page1496-1498
dc.identifier.isiutNOT_IN_WOS
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