Please use this identifier to cite or link to this item: https://doi.org/10.1023/A:1022059511261
DC FieldValue
dc.titlePreliminary study of a polycaprolactone membrane utilized as epidermal substrate
dc.contributor.authorKhor, H.L.
dc.contributor.authorNg, K.W.
dc.contributor.authorHtay, A.S.
dc.contributor.authorSchantz, J.-T.
dc.contributor.authorTeoh, S.H.
dc.contributor.authorHutmacher, D.W.
dc.date.accessioned2014-10-08T09:50:08Z
dc.date.available2014-10-08T09:50:08Z
dc.date.issued2003-02-01
dc.identifier.citationKhor, H.L., Ng, K.W., Htay, A.S., Schantz, J.-T., Teoh, S.H., Hutmacher, D.W. (2003-02-01). Preliminary study of a polycaprolactone membrane utilized as epidermal substrate. Journal of Materials Science: Materials in Medicine 14 (2) : 113-120. ScholarBank@NUS Repository. https://doi.org/10.1023/A:1022059511261
dc.identifier.issn09574530
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/88327
dc.description.abstractSolvent-cast sheets of polycaprolactone were biaxially stretched to produce 10-15 μm thick films. PCL films were found to have a tensile strength of 55 MPa which is about two and a half times stronger than native skin. One of our previous studies using non-coated PCL membranes showed that only 36% of the membrane surface was covered with keratinocytes after 9 days of culture. The present study examined the effects of coating the surface of PCL membranes with fibrin on the proliferation of keratinocytes. Qualitative analysis revealed that the cells attached and proliferated better on coated PCL films. Keratinocytes exhibited healthy cobblestone morphology and proliferated as continuous monolayers over a period of 16 days. The results indicated that fibrin coated PCL films would support the attachment and proliferation of human keratinocytes and have the potential to be applied as a matrix material for tissue engineering an epidermal equivalent. © 2003 Kluwer Academic Publishers.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1023/A:1022059511261
dc.sourceScopus
dc.typeConference Paper
dc.contributor.departmentMECHANICAL ENGINEERING
dc.contributor.departmentBIOENGINEERING
dc.contributor.departmentMATERIALS SCIENCE
dc.description.doi10.1023/A:1022059511261
dc.description.sourcetitleJournal of Materials Science: Materials in Medicine
dc.description.volume14
dc.description.issue2
dc.description.page113-120
dc.description.codenJSMME
dc.identifier.isiut000180392800004
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

33
checked on Jan 18, 2021

WEB OF SCIENCETM
Citations

32
checked on Jan 18, 2021

Page view(s)

77
checked on Jan 18, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.