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Title: Seed-mediated synthesis of NaY F4:Y b, Er/NaGdF4 nanocrystals with improved upconversion fluorescence and MR relaxivity
Authors: Guo, H.
Li, Z. 
Qian, H.
Hu, Y.
Muhammad, I.N. 
Issue Date: 2010
Citation: Guo, H., Li, Z., Qian, H., Hu, Y., Muhammad, I.N. (2010). Seed-mediated synthesis of NaY F4:Y b, Er/NaGdF4 nanocrystals with improved upconversion fluorescence and MR relaxivity. Nanotechnology 21 (12) : -. ScholarBank@NUS Repository.
Abstract: Rational combination of different functional lanthanide materials within a single nanocrystal presents a feasible way to develop a multifunctional nanoplatform for various biomedical applications. The conventional methods of synthesizing and integrating two kinds of material together generally involve laborious procedures, whilst codoping different functional ions inside a single lanthanide nanocrystal usually results in a decrease in both its fluorescence and its magnetic resonance relaxivity. Here, we present a seed-mediated synthetic route to prepare core-shell structured NaY F4:Y b, Er/NaGdF4 nanocrystals. Epitaxial growth of a gadolinium layer on an upconversion lanthanide seed not only improves its upconversion fluorescence, but also creates a paramagnetic shell with high magnetic resonance relaxivity. The prepared nanocrystals are uniform in size, stable in water and easy for conjugation after modification, which may have the potential to serve as a versatile imaging tool for smart detection or diagnosis in future biomedical engineering. © 2010 IOP Publishing Ltd.
Source Title: Nanotechnology
ISSN: 09574484
DOI: 10.1088/0957-4484/21/12/125602
Appears in Collections:Staff Publications

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