Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.actbio.2008.05.015
DC FieldValue
dc.titlePost-self-assembly experimentation on extruded collagen fibres for tissue engineering applications
dc.contributor.authorZeugolis, D.I.
dc.contributor.authorPaul, R.G.
dc.contributor.authorAttenburrow, G.
dc.date.accessioned2014-10-08T09:47:00Z
dc.date.available2014-10-08T09:47:00Z
dc.date.issued2008-11
dc.identifier.citationZeugolis, D.I., Paul, R.G., Attenburrow, G. (2008-11). Post-self-assembly experimentation on extruded collagen fibres for tissue engineering applications. Acta Biomaterialia 4 (6) : 1646-1656. ScholarBank@NUS Repository. https://doi.org/10.1016/j.actbio.2008.05.015
dc.identifier.issn17427061
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/88055
dc.description.abstractExtruded collagen fibres have been shown to constitute a biomimetic three-dimensional scaffold with numerous tissue engineering applications. The multi-step fabrication process of this material provides opportunities for further advancements to improve the properties of the final product. Herein we investigated the influence of the post-self-assembly washing baths on the structural, mechanical and thermal properties of these fibres. The surface morphology and the inter-fibre packing were similar for every treatment. The overnight incubation in isopropanol yielded fibres with the highest temperature and energy of denaturation (p < 0.013). Typical s- and j-shape stress-strain curves were obtained for all treatments in the dry and wet state respectively. Rehydration of the fibres resulted in increased fibre diameter (p < 0.006) and reduced stress (p < 0.001), force (p < 0.001) and modulus (p < 0.002) values for every treatment. In the dry state, the alcohol-treated fibres were characterized by the highest stress (p < 0.002) values; whilst in the wet state the Tris-HCl-treated fibres were the weakest (p < 0.006). For every treatment, in both dry and wet state, a strong and inverse relationship between the fibre diameter and the stress at break was observed. Overall, the fibres produced were characterized by properties similar to those of native tissues. © 2008 Acta Materialia Inc.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.actbio.2008.05.015
dc.sourceScopus
dc.subjectExtruded collagen fibres
dc.subjectMechanical properties
dc.subjectPost-self-assembly
dc.subjectStructural characteristics
dc.subjectThermal properties
dc.typeArticle
dc.contributor.departmentBIOENGINEERING
dc.description.doi10.1016/j.actbio.2008.05.015
dc.description.sourcetitleActa Biomaterialia
dc.description.volume4
dc.description.issue6
dc.description.page1646-1656
dc.identifier.isiut000261253400008
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

51
checked on Jan 26, 2022

WEB OF SCIENCETM
Citations

47
checked on Jan 19, 2022

Page view(s)

99
checked on Jan 27, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.