Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.bios.2010.07.030
DC Field | Value | |
---|---|---|
dc.title | Low-level detection of anti-cancer drug in blood plasma using microwave-treated gold-polystyrene beads as surface-enhanced Raman scattering substrates | |
dc.contributor.author | Yuen, C. | |
dc.contributor.author | Zheng, W. | |
dc.contributor.author | Huang, Z. | |
dc.date.accessioned | 2014-10-08T09:45:10Z | |
dc.date.available | 2014-10-08T09:45:10Z | |
dc.date.issued | 2010-10 | |
dc.identifier.citation | Yuen, C., Zheng, W., Huang, Z. (2010-10). Low-level detection of anti-cancer drug in blood plasma using microwave-treated gold-polystyrene beads as surface-enhanced Raman scattering substrates. Biosensors and Bioelectronics 26 (2) : 580-584. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bios.2010.07.030 | |
dc.identifier.issn | 09565663 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/87899 | |
dc.description.abstract | We report on a low-level detection of anti-cancer drug (paclitaxel) in blood plasma using microwave-treated gold (Au) film-polystyrene (PS) beads as surface-enhanced Raman scattering (SERS) substrates. SERS spectra of paclitaxel can be acquired within 10s at a concentration of 1×10-8M in blood plasma adsorbed on the modified Au-PS SERS substrates. The concentrations of paclitaxel ranging from 1.0×10-8 to 1.0×10-7M in blood plasma can be well estimated with an accuracy of ~3.8×10-9M using SERS technique. This work shows the promise of applying microwave-modified Au-PS as SERS substrates for rapid and accurate monitoring of the anti-cancer drug in blood plasma for immediate treatment decisions during cancer therapy. © 2010 Elsevier B.V. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.bios.2010.07.030 | |
dc.source | Scopus | |
dc.subject | Anti-cancer drug | |
dc.subject | Blood plasma | |
dc.subject | Cresyl violet | |
dc.subject | Paclitaxel | |
dc.subject | Polystyrene bead | |
dc.subject | Raman spectroscopy | |
dc.subject | Surface-enhanced Raman scattering | |
dc.type | Article | |
dc.contributor.department | BIOENGINEERING | |
dc.description.doi | 10.1016/j.bios.2010.07.030 | |
dc.description.sourcetitle | Biosensors and Bioelectronics | |
dc.description.volume | 26 | |
dc.description.issue | 2 | |
dc.description.page | 580-584 | |
dc.description.coden | BBIOE | |
dc.identifier.isiut | 000283804400044 | |
Appears in Collections: | Staff Publications |
Show simple item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.