Please use this identifier to cite or link to this item: https://doi.org/10.1117/1.JBO.18.3.030502
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dc.titleDevelopment of a multiplexing fingerprint and high wavenumber Raman spectroscopy technique for real-time in vivo tissue Raman measurements at endoscopy
dc.contributor.authorBergholt, M.S.
dc.contributor.authorZheng, W.
dc.contributor.authorHuang, Z.
dc.date.accessioned2014-10-08T09:43:26Z
dc.date.available2014-10-08T09:43:26Z
dc.date.issued2013
dc.identifier.citationBergholt, M.S., Zheng, W., Huang, Z. (2013). Development of a multiplexing fingerprint and high wavenumber Raman spectroscopy technique for real-time in vivo tissue Raman measurements at endoscopy. Journal of Biomedical Optics 18 (3) : -. ScholarBank@NUS Repository. https://doi.org/10.1117/1.JBO.18.3.030502
dc.identifier.issn10833668
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/87750
dc.description.abstractWe report on the development of a novel multiplexing Raman spectroscopy technique using a single laser light together with a volume phase holographic (VPH) grating that simultaneously acquires both fingerprint (FP) and high wavenumber (HW) tissue Raman spectra at endoscopy. We utilize a customized VPH dual-transmission grating, which disperses the incident Raman scattered light vertically onto two separate segments (i.e.,-150 to 1950 cm-1; 1750 to 3600 cm-1) of a charge-coupled device camera. We demonstrate that the multiplexing Raman technique can acquire high quality in vivo tissue Raman spectra ranging from 800 to 3600 cm-1 within 1.0 s with a spectral resolution of 3 to 6 cm-1 during clinical endoscopy. The rapid multiplexing Raman spectroscopy technique covering both FP and HW ranges developed in this work has potential for improving in vivo tissue diagnosis and characterization at endoscopy © 2013 The Authors.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1117/1.JBO.18.3.030502
dc.sourceScopus
dc.subjectendoscopy
dc.subjectin vivo
dc.subjectmultiplexing
dc.subjectRaman spectroscopy
dc.typeArticle
dc.contributor.departmentBIOENGINEERING
dc.description.doi10.1117/1.JBO.18.3.030502
dc.description.sourcetitleJournal of Biomedical Optics
dc.description.volume18
dc.description.issue3
dc.description.page-
dc.description.codenJBOPF
dc.identifier.isiut000322336700002
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