Please use this identifier to cite or link to this item: https://doi.org/10.1021/es7021363
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dc.titleMultivariate data analyses of persistent organic pollutants in maternal adipose tissue in Singapore
dc.contributor.authorTan, J.
dc.contributor.authorQing, Q.L.
dc.contributor.authorLoganath, A.
dc.contributor.authorYap, S.C.
dc.contributor.authorXiao, M.
dc.contributor.authorObbard, J.P.
dc.date.accessioned2014-10-08T08:33:01Z
dc.date.available2014-10-08T08:33:01Z
dc.date.issued2008-04-01
dc.identifier.citationTan, J., Qing, Q.L., Loganath, A., Yap, S.C., Xiao, M., Obbard, J.P. (2008-04-01). Multivariate data analyses of persistent organic pollutants in maternal adipose tissue in Singapore. Environmental Science and Technology 42 (7) : 2681-2687. ScholarBank@NUS Repository. https://doi.org/10.1021/es7021363
dc.identifier.issn0013936X
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/87566
dc.description.abstractPersistent organic pollutants (POPs) were detected in 88 maternal adipose tissue samples collected during year 2004 to 2006, in Singapore. Organochlorine pesticides (OCPs) were the most dominant followed by polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs). Multivariate data analyses (MVA) including principal component analysis (PCA), partial least-squares regression (PLSR), and partial least-squares discriminant analysis (PLS-DA) were applied to elucidate the relationship between concentrations of POPs in adipose tissues and donors' characteristics. Food consumption played the most significant role in accounting for levels of POPs in adipose tissue. Fish and poultry consumption was the route of PCBs and PBDEs in mothers in Singapore, while β-HCH came mainly from vegetables. An age-dependent accumulation of POPs was found for β-HCH and PCB congeners, and lactation and gestation functioned as a decontamination processes for PCBs in adipose tissue. Gestational diabetes mellitus (GDM) may change the profile of POPs in adipose tissue, probably due to an alteration in lipid metabolism. POPs investigated here may not be the cause of antenatal complication in pregnant women, and baby gender was not related to the pattern of contaminants in maternal adipose tissue. © 2008 American Chemical Society.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1021/es7021363
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentOBSTETRICS & GYNAECOLOGY
dc.contributor.departmentTROPICAL MARINE SCIENCE INSTITUTE
dc.contributor.departmentDIVISION OF ENVIRONMENTAL SCIENCE & ENGG
dc.description.doi10.1021/es7021363
dc.description.sourcetitleEnvironmental Science and Technology
dc.description.volume42
dc.description.issue7
dc.description.page2681-2687
dc.description.codenESTHA
dc.identifier.isiut000254492800076
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