Please use this identifier to cite or link to this item: https://doi.org/10.1007/978-3-540-92841-6_190
DC FieldValue
dc.titleMicrodevice for Trapping Circulating Tumor Cells for Cancer Diagnostics
dc.contributor.authorTan, S.J.
dc.contributor.authorYobas, L.
dc.contributor.authorLee, G.Y.H.
dc.contributor.authorOng, C.N.
dc.contributor.authorLim, C.T.
dc.date.accessioned2014-10-07T09:14:58Z
dc.date.available2014-10-07T09:14:58Z
dc.date.issued2009
dc.identifier.citationTan, S.J.,Yobas, L.,Lee, G.Y.H.,Ong, C.N.,Lim, C.T. (2009). Microdevice for Trapping Circulating Tumor Cells for Cancer Diagnostics. IFMBE Proceedings 23 : 774-777. ScholarBank@NUS Repository. <a href="https://doi.org/10.1007/978-3-540-92841-6_190" target="_blank">https://doi.org/10.1007/978-3-540-92841-6_190</a>
dc.identifier.isbn9783540928409
dc.identifier.issn16800737
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/86021
dc.description.abstractCancer metastasis is the main attribute to cancerrelated deaths and early detection is one of the most effective means to treat the disease. Spreading of cancer to distant sites is achieved usually through the circulatory system and the number of circulating tumor cells (CTCs) in peripheral blood is strongly associated to cancer development. Thus detecting CTCs in blood samples will be helpful in identifying susceptible subjects. Here, we propose a label-free technique to isolate these cancerous cells from blood. Using cancer cells spiked in blood samples, isolation efficiency of at least 80% were obtained with high isolation purity. The microdevice also preserved the integrity of the isolated cells to allow further studies to be done on these cells. These results showed a potential effective microdevice for CTCs studies and possible clinical application. © International Federation of Medical and Biological Engineering 2009.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1007/978-3-540-92841-6_190
dc.sourceScopus
dc.subjectCancer metastasis
dc.subjectCell isolation
dc.subjectCirculating tumor cells
dc.subjectComputational Fluid Dynamics (CFD)
dc.subjectMicrofluidics
dc.typeConference Paper
dc.contributor.departmentEPIDEMIOLOGY & PUBLIC HEALTH
dc.contributor.departmentMECHANICAL ENGINEERING
dc.description.doi10.1007/978-3-540-92841-6_190
dc.description.sourcetitleIFMBE Proceedings
dc.description.volume23
dc.description.page774-777
dc.identifier.isiutNOT_IN_WOS
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