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https://doi.org/10.1039/c2cc31294h
Title: | Ugi reaction-assisted rapid assembly of affinity-based probes against potential protein tyrosine phosphatases | Authors: | Ge, J. Cheng, X. Tan, L.P. Yao, S.Q. |
Issue Date: | 11-May-2012 | Citation: | Ge, J., Cheng, X., Tan, L.P., Yao, S.Q. (2012-05-11). Ugi reaction-assisted rapid assembly of affinity-based probes against potential protein tyrosine phosphatases. Chemical Communications 48 (37) : 4453-4455. ScholarBank@NUS Repository. https://doi.org/10.1039/c2cc31294h | Abstract: | The multi-component Ugi reaction has been employed to assemble a small library of affinity-based probes (AfBPs) that target potential protein tyrosine phosphatases. The probes showed good labelling of PTP1B and MptpB, and were subsequently used to label endogenous PTP1B in MCF-7 cell lysates. © 2012 The Royal Society of Chemistry. | Source Title: | Chemical Communications | URI: | http://scholarbank.nus.edu.sg/handle/10635/77330 | ISSN: | 13597345 | DOI: | 10.1039/c2cc31294h |
Appears in Collections: | Staff Publications |
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