Please use this identifier to cite or link to this item:
https://doi.org/10.1021/ac0302354
DC Field | Value | |
---|---|---|
dc.title | Two-Step Liquid-Liquid-Liquid Microextraction of Nonsteroidal Antiinflammatory Drugs in Wastewater | |
dc.contributor.author | Wen, X. | |
dc.contributor.author | Tu, C. | |
dc.contributor.author | Lee, H.K. | |
dc.date.accessioned | 2014-06-23T05:53:42Z | |
dc.date.available | 2014-06-23T05:53:42Z | |
dc.date.issued | 2004-01-01 | |
dc.identifier.citation | Wen, X., Tu, C., Lee, H.K. (2004-01-01). Two-Step Liquid-Liquid-Liquid Microextraction of Nonsteroidal Antiinflammatory Drugs in Wastewater. Analytical Chemistry 76 (1) : 228-232. ScholarBank@NUS Repository. https://doi.org/10.1021/ac0302354 | |
dc.identifier.issn | 00032700 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/77329 | |
dc.description.abstract | A simple and novel two-step liquid-liquid-liquid microextraction technique combined with reversed-phase HPLC has been developed for the determination of the nonsteroidal antiinflammatory drugs ibuprofen and 2-(4-chlorophenoxy)-2-methylpropionic acid in wastewater samples. In the first step, the analytes were extracted from an acidified sample (donor solution) into 1-octanol immobilized in the pores of 10 pieces of polypropylene hollow fiber and further into a basic acceptor phase inside the hollow fiber channels. This first extraction step, using 0.01 M NaOH as the acceptor phase and 0.1 M HCl within the donor phase, had a 100% relative recovery with an enrichment factor of 100-fold. The extract in the first step was then adjusted to acidic condition with HCl. It now represented the donor phase for the second step of the extraction, using a single piece of hollow fiber, with 2 μL of 0.01 M NaOH solution as the acceptor phase. This analyte-enriched acceptor phase was subsequently withdrawn into a microsyringe and directly injected into an HPLC system for analysis. With this two-step microextraction, sensitivity enhancement of > 15 000-fold could be obtained. Detection limits of ≤ 100 ng/L could be achieved for both compounds. The method was applied to the analysis of wastewater. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1021/ac0302354 | |
dc.source | Scopus | |
dc.type | Article | |
dc.contributor.department | CHEMISTRY | |
dc.description.doi | 10.1021/ac0302354 | |
dc.description.sourcetitle | Analytical Chemistry | |
dc.description.volume | 76 | |
dc.description.issue | 1 | |
dc.description.page | 228-232 | |
dc.description.coden | ANCHA | |
dc.identifier.isiut | 000187806100035 | |
Appears in Collections: | Staff Publications |
Show simple item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.