Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imaging

Please use this identifier to cite or link to this item: https://doi.org/10.1039/c1cc11253h

Title:	Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imaging
Authors:	Lee, J.H. So, J.-H. Jeon, J.H. Choi, E.B. Lee, Y.-R. Chang, Y.-T. Kim, C.-H. Bae, M.A. Ahn, J.H.
Issue Date:	14-Jul-2011
Citation:	Lee, J.H., So, J.-H., Jeon, J.H., Choi, E.B., Lee, Y.-R., Chang, Y.-T., Kim, C.-H., Bae, M.A., Ahn, J.H. (2011-07-14). Synthesis of a new fluorescent small molecule probe and its use for in vivo lipid imaging. Chemical Communications 47 (26) : 7500-7502. ScholarBank@NUS Repository. https://doi.org/10.1039/c1cc11253h
Abstract:	A new small molecule probe for in vivo lipid imaging, LipidGreen (compound 5), was developed. LipidGreen stained lipid droplets in 3T3L1 cell lines and fat deposits in zebrafish without apparent toxicity up to 100 μM. The utility of LipidGreen as a drug screening platform for fat regulation was also demonstrated in live zebrafish. © 2011 The Royal Society of Chemistry.
Source Title:	Chemical Communications
URI:	http://scholarbank.nus.edu.sg/handle/10635/77173
ISSN:	13597345
DOI:	10.1039/c1cc11253h
Appears in Collections:	Staff Publications

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