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Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.tetlet.2012.03.071
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dc.titleSynthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins
dc.contributor.authorGhosh, S.K.
dc.contributor.authorButler, M.S.
dc.contributor.authorLear, M.J.
dc.date.accessioned2014-06-23T05:51:43Z
dc.date.available2014-06-23T05:51:43Z
dc.date.issued2012-05-30
dc.identifier.citationGhosh, S.K., Butler, M.S., Lear, M.J. (2012-05-30). Synthesis of 2-C-methylerythritols and 2-C-methylthreitols via enantiodivergent Sharpless dihydroxylation of trisubstituted olefins. Tetrahedron Letters 53 (22) : 2706-2708. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2012.03.071
dc.identifier.issn00404039
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/77169
dc.description.abstractThe mevalonate-independent pathway (MIP) is an interesting avenue for antimicrobial lead discovery. Here, we present a unified enantioselective synthesis of all four stereoisomers of 2-C-methyltetrol. These are useful building blocks of many bioactive natural products, including 2-C-methylerythritol phosphate (MEP) of the MIP biosynthetic pathway. © 2012 Elsevier Ltd. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.tetlet.2012.03.071
dc.sourceScopus
dc.subjectAntibiotic
dc.subjectDudley
dc.subjectEnantiodivergent
dc.subjectErythritol
dc.subjectMalaria
dc.subjectMevalonate
dc.subjectMicrobial
dc.subjectParasitic
dc.subjectSharpless
dc.subjectTetraols
dc.subjectThreitol
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1016/j.tetlet.2012.03.071
dc.description.sourcetitleTetrahedron Letters
dc.description.volume53
dc.description.issue22
dc.description.page2706-2708
dc.description.codenTELEA
dc.identifier.isiut000303953200008
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